the world of future medical technology
Trend report (No 2)
New synthetic particles stop blood supply to tumours
Innovative materials have always been an important topic at the COMPAMED. What can be achieved with innovative materials has been proven just recently by Dr Ulrike Stampfl, radiologist at the Heidelberg University Hospital. A starting point for a new type of cancer therapy procedure are tiny artificial particles combined with a low level of embedded metal. With so-called embolisation, these particles are introduced into the blood vessels of a tumour using a catheter. They seal the blood vessels leading to the inner portion of the tumour and block its oxygen and nutrient supply - the tumour becomes responsive to subsequent medicative therapy. Positioning the catheter and releasing the particles are carried out under X-ray control. For a long time, contrast agents had to be used along with the particles due to the fact that they were not visible against the background environment of the fluoroscopy. Thanks to the embedded metal, X-rays are not able to penetrate these new particles, making them easy to see in addition to generating signals in the magnetic resonance tomography (MRT). "Our tests have shown that the new particles are indeed very easy to see using various imaging techniques. Therefore, they increase the level of control during the intervention itself and for the post-control examinations using MRT and computer tomography. We can directly examine how the particles disperse within the vessels," explained Dr Stampfl, a senior physician that had been awarded the Werner-Porstmann Prize by the German Radiological Society (DRG).
Package small batches quickly flexibly and safely
The packaging industry also remains a "never-ending hot topic" at the COMPAMED. The packaging and production process in the medical goods and healthcare industry are dominated by a single trend in particular: individualisation with regard to package contents and labelling. In this way, medical and healthcare products are increasingly tailored to local markets and patient needs. Consequent to this development, the production batches are getting smaller and smaller. By means of this, there are many more production line changes to accommodate different batches. Therefore, packaging solutions with reliable processes are in demand that are especially flexible. Against this backdrop, Multivac has developed several compact models such as the T 260 Traysealer, the C 400 TC special chamber machine and the R 145 thermoform packaging machine. All of these will be presented in Düsseldorf. "A high level of process reliability for packaging plays a crucial role in achieving high quality when manufacturing healthcare and life-science products. Our packaging and labelling solutions that we have designed for the industry support processes to provide reliable 'line clearance' when changing over production lines to accommodate for batch changes in addition to providing product counterfeit protection and traceability of processes. In the same way, our devices ensure simple and reliable user guidance," explained Verena Weiss, product manager for MCP (medial, cosmetics and pharmaceutical products) at Multivac. With regard to the thermoform packaging machine, the machine concept has been optimised in terms of providing reliable line clearance. Process and technical rooms are separated from each other to a great extent. All assembly units, including hoses, cables and valves, have been repositioned away from the internal part of the machine to the backside of it. In this way, the risk is reduced that products get stuck in the internal part of the machine during the packaging process, thus causing the machine to stop.
New diagnostic systems for detecting the colonization of germs on the skin
Thanks to its variety, time and again, the COMPAMED is also good for new applications using the generally known means available. This said, the CiS research institute for microsensor technology and photovoltaics is presenting innovative applications for UV light. Under the title, "Advanced UV for Life", eight research facilities and 14 industrial companies have formed a cooperation to take advantage of high-energy radiation. The project is being promoted within the scope of the high-tech strategy and has the aim of developing new UV LED light sources that can also be applied in the field of medicine and medical technology. There are uses in the fields of dermatology, phototherapy, blood analysis and microbial detection. The CiS also shares the responsibility for developing integrated optical and impedimetric sensors as well as constructing microsystems based on UV LED components and silicium detectors for UV radiation. In particular, for a precise diagnosis, new diagnostic systems are required to detect germ colonisation on the skin that are capable of defining the germ class and germ count quickly and reliably. Therefore, innovative miniaturised UV technology coupled with biomedical sensors is necessary. Thus, sensor solutions are needed that use different optical spectroscopic methods such as UV remission, fluorescence or impedance spectroscopy as multi-sensor system.
from 20 to 22 November. 2013, Fair ground Dusseldorf (Germany)
Image: R. Eberhard, messekompakt, EBERHARD print & medien agentur gmbh
Source: Messe Düsseldorf